The latest advancement in integrated ion chromatography (IC) instrumentation, the Thermo Scientific Dionex Integrion HPIC system, can operate continuously up to 5000 psi for both 4 mm and 2 mm i.d. column formats with automated eluent generation and 6000 psi with manual eluent preparation. These higher pressures allow the analyst to take full advantage of the high efficiency and fast separations offered by smaller particle size separation columns.